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SUMMARY:BE-STEMM Seminar: Exploring the differences in carbohydrate binding coronaviruses that cause human disease
DESCRIPTION:Join us for our second seminar of the 2023/2024 Academic year. \nOctober 18\, 4pm ET \nZaky Hassan\nPhD Candidate\, University of Toronto \n  \nBio: \nZaky is a fourth year PhD candidate in the Biochemistry department at the University of Toronto. He previously completed an HBSc in Biochemistry also from the University of Toronto. Outside of the lab\, Zaky works with Visions of Science as a community coordinator\, creating and facilitating programming focused on improving STEM accessibility for Black students in highschool and postsecondary. \nExploring the differences in carbohydrate binding coronaviruses that cause human disease\nCoronaviruses are a family of viruses that cause disease in mammals and birds and can be categorized into two groups – those that use proteins as receptors and those that use sugars (carbohydrates) as receptors. For protein binding coronaviruses\, we have a good understanding of how they interact with their receptors\, and how they enter our cells. For carbohydrate binding coronaviruses however\, we have a very limited understanding of the receptors they use beyond a requirement for sialic acid\, a type of sugar commonly found on cell surfaces. Our previous work has shown that various strains of carbohydrate binding coronaviruses have differences in their sugar binding site – resulting in different preferences for various sialylated carbohydrates. Using structural\, biochemical\, and biophysical tools\, we are identifying the various types of receptors used by these viruses\, and investigating the mechanism of receptor interaction.  Our work will shed light on the receptor interactions for a disease causing group of viruses with pandemic potential that are relatively understudied\, and will hopefully lay the groundwork for future vaccine and therapeutic development. \n——————– \nOur monthly online seminar series\, features STEMM scholarship from across disciplines\, aimed at a general STEMM audience. \nAll are welcome! \n\n4pm ET\nThird Wednesday of every month\nSeptember 2024 through April 2024.\n\nRegister once and we will remind you each month. \n \nWatch this space for seminar speaker announcements! \n\nSeptember 20\nOctober 18\nNovember 15\nDecember 20\nJanuary 17\nFebruary 21\nMarch 20\nApril 17\n\n\nThe CBSN/RCSN gratefully acknowledges the University of Toronto Scarborough and its support as the Network Host Institution\, and the Academic Program Committee of the Network for the BE-STEMM Seminar Series.
URL:https://blackscientists.ca/be-stemm-event/be-stemm-seminar-exploring-the-differences-in-carbohydrate-binding-coronaviruses-that-cause-human-disease/
LOCATION:Zoom\, Canada
CATEGORIES:BE-STEMM Seminar
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